Sulfhydryl-dependent thermal aggregation of human gamma globulin

Human Gamma Globulin.

Structural units of human 7S gamma globulin.

Immunoglobulin Components of "gamma" Globulin in Human Serum.

Forty blood samples were obtame(1 from 36 subjects who ranged ill age from 3 days to 43 years. All subjects were examined! on tile day blood was drawn; the health of each was noted. Each serum sample was analyzed for immunoglobulins y G, y A, aIld y M by the agar gel precipitation method described by Claman and Merrill (2). In this test, serum is layered over a column of agar containing an anti...

Gamma globulin prophylaxis.

THE importance of infectious hepatitis as a world-wide problem has been highlighted in detail during the presentations made at this symposium. It is clear that as of today (May I 8, I968) there is no published report confirming the isolation of infectious hepatitis virus in a tissue-culture system or animal host. Experience with poliomyelitis, measles, and rubella has revealed that the time int...

Adsorption and Aggregation of Gamma Globulin onto Chylomicrons in Serum of Lowered Ionic Strength †

In the course of experiments involving centrifugation of fresh postprandial human serum diluted with isotonic sucrose, an unexpected phenomenon was noted; the usual opaque fat layer at the surface was missing, and a white pellet was deposited at the bottom of the tube. Microscopic and chemical examinations revealed the deposit to be composed of chylomicrons. Further study of this phenomenon dem...